Interferon-α signaling promotes embryonic HSC maturation-Reference-Cited by-同舟云学术

Interferon-α signaling promotes embryonic HSC maturation

Published:2016-07-14 Issue:2 Volume:128 Page:204-216
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Kim Peter Geon¹²³,Canver Matthew C.¹,Rhee Catherine⁴,Ross Samantha J.¹²³,Harriss June V.⁴,Tu Ho-Chou¹²³,Orkin Stuart H.¹,Tucker Haley O.⁴,Daley George Q.¹²³

Affiliation:

1. Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA;

2. Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, MA;

3. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA; and

4. Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX

Abstract

Key Points INF-α promotes engraftment of mid-gestation HSCs. INF-α can restore the hematopoietic defect of Arid3a knockout embryos.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/128/2/204/1396941/204.pdf

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