Circulating T follicular helper cells with increased function during chronic graft-versus-host disease-Reference-Cited by-同舟云学术

Circulating T follicular helper cells with increased function during chronic graft-versus-host disease

Published:2016-05-19 Issue:20 Volume:127 Page:2489-2497
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Forcade Edouard¹²³,Kim Haesook T.⁴⁵,Cutler Corey¹²,Wang Kathy¹²,Alho Ana C.¹²,Nikiforow Sarah¹²,Ho Vincent T.¹²,Koreth John¹²,Armand Philippe¹²,Alyea Edwin P.¹²,Blazar Bruce R.⁶,Soiffer Robert J.¹²,Antin Joseph H.¹²,Ritz Jerome¹²⁷

Affiliation:

1. Division of Hematologic Malignancies and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA;

2. Harvard Medical School, Boston, MA;

3. UMR CNRS 5164, Bordeaux University, Bordeaux, France;

4. Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA;

5. Harvard School of Public Health, Boston, MA;

6. Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis, MN; and

7. Cancer Vaccine Center, Dana-Farber Cancer Institute, Boston, MA

Abstract

Key Points cTFH are activated and skewed toward a Th2/Th17 phenotype promoting their B-cell help function during cGVHD. cTFH activation signature correlates with memory B-cell and plasmablast phenotype in cGVHD patients.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/127/20/2489/1393266/2489.pdf

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