1. Centre for Clinical Pharmacology and Therapeutics and
2. Centre for Cardiovascular Biology and Medicine, Division of Medicine, University College London, London, United Kingdom;
3. Department of Molecular Cell Biology, Vrije Universiteit, VUMC, Amsterdam, The Netherlands;
4. Centre for Molecular Medicine, Division of Medicine, University College London, London, United Kingdom;
5. St Helier Hospital, Carshalton, Surrey, United Kingdom; and
6. Respiratory Centre of Excellence in Drug Discovery, GlaxoSmithKline, Stevenage, United Kingdom