Evidence that fibrinogen γ′ regulates plasma clot structure and lysis and relationship to cardiovascular risk factors in black Africans-Reference-Cited by-同舟云学术

Evidence that fibrinogen γ′ regulates plasma clot structure and lysis and relationship to cardiovascular risk factors in black Africans

Published:2013-04-18 Issue:16 Volume:121 Page:3254-3260
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Pieters Marlien¹,Kotze Retha C.¹,Jerling Johann C.¹,Kruger Annamarie²,Ariëns Robert A. S.³

Affiliation:

1. Centre of Excellence for Nutrition and

2. Africa Unit for Transdisciplinary Health Research, North-West University, Potchefstroom, South Africa; and

3. Theme Thrombosis, Division of Cardiovascular and Diabetes Research, Multidisciplinary Cardiovascular Research Centre and Leeds Institute for Genetics, Health and Therapeutics, School of Medicine, University of Leeds, Leeds, United Kingdom

Abstract

Key PointsThis paper describes the effect of fibrinogen γ′ on clot structure in plasma (previously shown in purified systems). This paper also describes the respective roles of total fibrinogen, fibrinogen γ′ concentration, and ratio on clot structure and lysis rates.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/16/3254/1329203/3254.pdf

Reference34 articles.

1. Demonstration of a large molecular weight variant of the gamma chain of normal human plasma fibrinogen.;Francis;J Biol Chem,1980

2. Human plasma fibrinogen heterogeneity: evidence for an extended carboxyl-terminal sequence in a normal gamma chain variant (gamma’).;Wolfenstein-Todel;Proc Natl Acad Sci USA,1980

3. gamma and gamma’ chains of human fibrinogen are produced by alternative mRNA processing.;Chung;Biochemistry,1984

4. Structure of the human gamma-fibrinogen gene. Alternate mRNA splicing near the 3′ end of the gene produces gamma A and gamma B forms of gamma-fibrinogen.;Fornace;J Biol Chem,1984

5. Genetic variation in the fibrinogen gamma gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen gamma’ levels.;Uitte de Willige;Blood,2005

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