Elevated CXCL1 expression in gp130-deficient endothelial cells impairs neutrophil migration in mice-Reference-Cited by-同舟云学术

Elevated CXCL1 expression in gp130-deficient endothelial cells impairs neutrophil migration in mice

Published:2013-11-28 Issue:23 Volume:122 Page:3832-3842
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Yao Longbiao¹,Yago Tadayuki¹,Shao Bojing¹,Liu Zhenghui¹,Silasi-Mansat Robert¹,Setiadi Hendra¹,Lupu Florea¹²,McEver Rodger P.¹³

Affiliation:

1. Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK; and

2. Departments of Pathology and

3. Biochemistry & Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK

Abstract

Key Points Elevated CXCL1 expression on gp130-deficient endothelial cells triggers neutrophil arrest but impairs transendothelial migration. Loss of endothelial cell gp130 dysregulates integrin-dependent adhesion and de-adhesion of neutrophils during inflammation.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/23/3832/1464749/3832.pdf

Reference49 articles.

1. Getting to the site of inflammation: the leukocyte adhesion cascade updated.;Ley;Nat Rev Immunol,2007

2. Neutrophil-active chemokines in in vivo imaging of neutrophil trafficking.;Sanz;Eur J Immunol,2012

3. The neutrophil in vascular inflammation.;Phillipson;Nat Med,2011

4. Rolling cell adhesion.;McEver;Annu Rev Cell Dev Biol,2010

5. Neutrophil arrest by LFA-1 activation.;Lefort;Front Immunol,2012

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