Transfusion suppresses erythropoiesis and increases hepcidin in adult patients with β-thalassemia major: a longitudinal study

Abstract

Key Points In β-thalassemia major, hepcidin levels are simultaneously associated with erythropoiesis and iron loading pre- and posttransfusion. Transfusion improves anemia, suppressing erythropoiesis and in turn increasing hepcidin in patients with β-thalassemia major.