Human neutrophils mediate trogocytosis rather than phagocytosis of CLL B cells opsonized with anti-CD20 antibodies-Reference-Cited by-同舟云学术

Human neutrophils mediate trogocytosis rather than phagocytosis of CLL B cells opsonized with anti-CD20 antibodies

Published:2017-05-11 Issue:19 Volume:129 Page:2636-2644
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Valgardsdottir Rut¹^ORCID,Cattaneo Irene²,Klein Christian³,Introna Martino¹,Figliuzzi Marina²,Golay Josée¹^ORCID

Affiliation:

1. Center of Cellular Therapy G. Lanzani, Division of Hematology, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy;

2. Department of Biomedical Engineering, Istituto di Ricerche Farmacologiche Mario Negri, Istituto di Ricovero e Cura a Carattere Scientifico, Bergamo, Italy; and

3. Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland

Abstract

Key Points Human neutrophils mediate trogocytosis rather than phagocytosis of CD20-antibody–opsonized CLL B cells. Trogocytosis is induced more effectively by rituximab compared with obinutuzumab.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/19/2636/1400406/blood735605.pdf

Reference37 articles.

1. Neutrophils mediate antibody-induced antitumor effects in mice;Albanesi;Blood,2013

2. Neutrophils contribute to the biological antitumor activity of rituximab in a non-Hodgkin’s lymphoma severe combined immunodeficiency mouse model;Hernandez-Ilizaliturri;Clin Cancer Res,2003

3. The CCL3 family of chemokines and innate immunity cooperate in vivo in the eradication of an established lymphoma xenograft by rituximab;Cittera;J Immunol,2007

4. Glycoengineered CD20 antibody obinutuzumab activates neutrophils and mediates phagocytosis through CD16B more efficiently than rituximab;Golay;Blood,2013

5. CD20 antibodies induce production and release of reactive oxygen species by neutrophils;Werlenius;Blood,2014

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