Platelets activate a pathogenic response to blood-stage Plasmodium infection but not a protective immune response-Reference-Cited by-同舟云学术

Platelets activate a pathogenic response to blood-stage Plasmodium infection but not a protective immune response

Published:2017-03-23 Issue:12 Volume:129 Page:1669-1679
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Gramaglia Irene¹,Velez Joyce¹,Combes Valery¹²,Grau Georges E. R.¹³,Wree Melanie⁴,van der Heyde Henri C.¹

Affiliation:

1. La Jolla Infectious Disease Institute, San Diego, CA;

2. School of Life Sciences, University of Technology Sydney, Sydney, Australia;

3. Vascular Immunology Unit, University of Sydney, Sydney, Australia; and

4. University of California San Diego, San Diego, CA

Abstract

Key Points Platelets are not killer cells of blood-stage Plasmodium parasites. Platelets are not required to activate the protective immune response to blood-stage Plasmodium infection in mice.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/12/1669/1399445/blood733519.pdf

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4. Platelets kill intraerythrocytic malarial parasites and mediate survival to infection;McMorran;Science,2009

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