CXCR7-dependent angiogenic mononuclear cell trafficking regulates tumor progression in multiple myeloma-Reference-Cited by-同舟云学术

CXCR7-dependent angiogenic mononuclear cell trafficking regulates tumor progression in multiple myeloma

Published:2014-09-18 Issue:12 Volume:124 Page:1905-1914
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Azab Abdel Kareem¹²,Sahin Ilyas¹,Azab Feda¹²,Moschetta Michele¹,Mishima Yuji¹,Burwick Nicholas¹,Zimmermann Johann³,Romagnoli Barbara³,Patel Kalpana³,Chevalier Eric³,Roccaro Aldo M.¹,Ghobrial Irene M.¹

Affiliation:

1. Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA;

2. Cancer Biology Division, Department of Radiation Oncology, Washington University in St. Louis, St. Louis, MO; and

3. Polyphor Ltd., Allschwil, Switzerland

Abstract

Key Points AMCs home to tumor sites in MM. CXCR7 inhibition delayed tumor progression in MM through specific regulation of AMC trafficking but not through a direct tumor effect.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/124/12/1905/1380109/1905.pdf

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