RhoA determines disease progression by controlling neutrophil motility and restricting hyperresponsiveness-Reference-Cited by-同舟云学术

RhoA determines disease progression by controlling neutrophil motility and restricting hyperresponsiveness

Author:

Jennings Richard T.¹,Strengert Monika¹,Hayes Patti¹,El-Benna Jamel²,Brakebusch Cord³,Kubica Malgorzata¹,Knaus Ulla G.¹

Affiliation:

1. Conway Institute, School of Medicine and Medical Science, University College Dublin, Dublin, United Kingdom;

2. INSERM U773, Université Paris 7 Denis Diderot, Sorbonne Paris Cité, Laboratoire d’Excellence Inflamex, Paris, France; and

3. Biomedical Institute, Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark

Abstract

Key Points Rho-deficient neutrophils are hyperresponsive. RhoA acts predominantly as a negative regulator of chemotaxis.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

Reference52 articles.

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