Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression-Reference-Cited by-同舟云学术

Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression

Published:2015-12-24 Issue:26 Volume:126 Page:2811-2820
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Anderson Heidi¹²,Patch Taylor C.¹,Reddy Pavankumar N. G.²³,Hagedorn Elliott J.²³,Kim Peter G.³,Soltis Kathleen A.¹,Chen Michael J.²³,Tamplin Owen J.²³,Frye Maike⁴,MacLean Glenn A.²³,Hübner Kathleen¹,Bauer Daniel E.²³⁵,Kanki John P.⁶,Vogin Guillaume¹,Huston Nicholas C.¹,Nguyen Minh³,Fujiwara Yuko²³,Paw Barry H.¹²³,Vestweber Dietmar⁴,Zon Leonard I.²³⁵⁷,Orkin Stuart H.²³⁵⁶⁷,Daley George Q.²³⁵⁷,Shah Dhvanit I.¹²⁵^ORCID

Affiliation:

1. Division of Hematology, Department of Medicine, Brigham and Women’s Hospital, Boston, MA;

2. Harvard Medical School, Boston, MA;

3. Division of Hematology/Oncology, Boston Children’s Hospital, Boston, MA;

4. Max Planck Institute for Molecular Biomedicine, Münster, Germany;

5. Harvard Stem Cell Institute, Cambridge, MA;

6. Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA; and

7. Howard Hughes Medical Institute, Boston, MA

Abstract

Key Points HSCs emerge, engraft, and differentiate in the absence of cdh5. HSCs emerging from Cdh5−/−GFP+/+ endothelium of mouse chimeric embryos are functional.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/126/26/2811/1390840/2811.pdf

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5. Embryonic stem cell differentiation as a model to study hematopoietic and endothelial cell development.;Fraser;Methods Mol Biol,2002

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