Detection of septic transfusion reactions to platelet transfusions by active and passive surveillance

Author:

Hong Hong1,Xiao Wenbin1,Lazarus Hillard M.1ORCID,Good Caryn E.1,Maitta Robert W.1ORCID,Jacobs Michael R.1

Affiliation:

1. Departments of Pathology and Medicine, University Hospitals Case Medical Center and Case Western Reserve University School of Medicine, Cleveland, OH

Abstract

Key Points Bacterial sepsis from contaminated platelet transfusions continues to occur despite recent interventions; additional measures are needed. STR to platelet transfusion is frequently not recognized or reported; use of recent AABB criteria showed highest diagnostic sensitivity.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Reference35 articles.

1. Platelet transfusion: a clinical practice guideline from the AABB.;Kaufman;Ann Intern Med,2015

2. US Department of Health and Human Services The 2011 National Blood Collection and Utilization Survey Report. Available at: http://www.hhs.gov/ash/bloodsafety/2011-nbcus.pdf. Accessed November 20, 2015

3. Addressing the risk of bacterial contamination of platelets within the United States: a history to help illuminate the future.;Brecher;Transfusion,2013

4. US Food and Drug Administration Fatalities Reported to FDA Following Blood Collection and Transfusion: Annual Summary for Fiscal Year 2013. http://www.fda.gov/BiologicsBloodVaccines/SafetyAvailability/ReportaProblem/TransfusionDonationFatalities/ucm391574.htm. Accessed November 20, 2015

5. AABB Clinical Recognition and Investigation of Suspected Bacterial Contamination of Platelets. AABB Association Bulletin #14-04. http://www.aabb.org/programs/publications/bulletins/Documents/ab14-04.pdf. Accessed November 20, 2015

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