MUC1-C drives MYC in multiple myeloma-Reference-Cited by-同舟云学术

MUC1-C drives MYC in multiple myeloma

Published:2016-05-26 Issue:21 Volume:127 Page:2587-2597
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Tagde Ashujit¹,Rajabi Hasan¹,Bouillez Audrey¹,Alam Maroof¹,Gali Reddy²,Bailey Shannon¹,Tai Yu-Tzu¹,Hideshima Teru¹,Anderson Kenneth¹,Avigan David³,Kufe Donald¹

Affiliation:

1. Department of Medical Oncology, Dana-Farber Cancer Institute,

2. Department of Biomedical Informatics, and

3. Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA

Abstract

Key Points MUC1-C induces MYC gene transcription in MM cells. Targeting MUC1-C downregulates MYC expression and its transcriptional program.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/127/21/2587/1394136/2587.pdf

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