In vitro culture of stress erythroid progenitors identifies distinct progenitor populations and analogous human progenitors-Reference-Cited by-同舟云学术

In vitro culture of stress erythroid progenitors identifies distinct progenitor populations and analogous human progenitors

Published:2015-03-12 Issue:11 Volume:125 Page:1803-1812
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Xiang Jie¹,Wu Dai-Chen²,Chen Yuanting¹,Paulson Robert F.¹²³

Affiliation:

1. Graduate Program in Molecular, Cellular and Integrative Biosciences,

2. Graduate Program in Biochemistry, Microbiology and Molecular Biology, and

3. Center for Molecular Immunology and Infectious Disease, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA

Abstract

Key Points Murine stress erythroid progenitors develop through a series of progenitors that express CD34, CD133, Kit, and Sca1. Human stress erythroid progenitors can be expanded using the same culture system and are predisposed to express γ-globin.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/125/11/1803/1384443/1803.pdf

Reference36 articles.

1. Stress erythropoiesis: new signals and new stress progenitor cells.;Paulson;Curr Opin Hematol,2011

2. Extramedullary erythropoiesis in the adult liver requires BMP-4/Smad5-dependent signaling.;Lenox;Exp Hematol,2009

3. BMP4/Smad5 dependent stress erythropoiesis is required for the expansion of erythroid progenitors during fetal development.;Porayette;Dev Biol,2008

4. BMP4, SCF, and hypoxia cooperatively regulate the expansion of murine stress erythroid progenitors.;Perry;Blood,2007

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