Plasma exchange to remove HIT antibodies: dissociation between enzyme-immunoassay and platelet activation test reactivities-Reference-Cited by-同舟云学术

Plasma exchange to remove HIT antibodies: dissociation between enzyme-immunoassay and platelet activation test reactivities

Published:2015-01-01 Issue:1 Volume:125 Page:195-198
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Warkentin Theodore E.¹²,Sheppard Jo-Ann I.¹,Chu F. Victor³,Kapoor Anil³,Crowther Mark A.¹²,Gangji Azim²

Affiliation:

1. Department of Pathology and Molecular Medicine,

2. Department of Medicine, and

3. Department of Surgery, McMaster University, Hamilton, ON, Canada

Abstract

Key Points Repeated plasma exchange removes sufficient HIT-IgG to achieve negative SRA despite ongoing strong-positive EIA. Serially-diluted HIT sera tested in both SRA and EIA show that SRA negativity can be achieved with minimal decrease in EIA reactivity.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/125/1/195/1383451/195.pdf

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