Association between diffuse myocardial fibrosis and diastolic dysfunction in sickle cell anemia-Reference-Cited by-同舟云学术

Association between diffuse myocardial fibrosis and diastolic dysfunction in sickle cell anemia

Published:2017-07-13 Issue:2 Volume:130 Page:205-213
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Niss Omar¹,Fleck Robert²,Makue Fowe³,Alsaied Tarek³,Desai Payal⁴,Towbin Jeffrey A.⁵,Malik Punam¹⁶,Taylor Michael D.³,Quinn Charles T.¹

Affiliation:

1. Division of Hematology,

2. Department of Radiology, and

3. Division of Cardiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH;

4. Department of Internal Medicine, The Ohio State University, Columbus, OH;

5. The Heart Institute, Le Bonheur Children’s Hospital, Memphis, TN; and

6. Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Abstract

Key Points Diffuse myocardial fibrosis is a common and novel mechanism of heart disease in SCA that can be detected noninvasively. Diffuse myocardial fibrosis is strongly associated with diastolic dysfunction in individuals with SCA.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/130/2/205/1404213/blood767624.pdf

Reference50 articles.

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4. Pulmonary hypertension as a risk factor for death in patients with sickle cell disease;Gladwin;N Engl J Med,2004

5. Cardiomyopathy with restrictive physiology in sickle cell disease;Niss;JACC Cardiovasc Imaging,2016

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