Lower levels of vitamin A are associated with increased gastrointestinal graft-versus-host disease in children-Reference-Cited by-同舟云学术

Lower levels of vitamin A are associated with increased gastrointestinal graft-versus-host disease in children

Published:2017-05-18 Issue:20 Volume:129 Page:2801-2807
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Lounder Dana T.¹,Khandelwal Pooja¹,Dandoy Christopher E.¹,Jodele Sonata¹,Grimley Michael S.¹,Wallace Gregory¹,Lane Adam¹,Taggart Cynthia²,Teusink-Cross Ashley C.³,Lake Kelly E.¹,Davies Stella M.¹

Affiliation:

1. Division of Bone Marrow Transplant and Immune Deficiency,

2. Division of Nutrition Therapy, and

3. Department of Pharmacy, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

Abstract

Key Points Vitamin A levels below the median at day 30 posttransplant are associated with increased cumulative incidence of GI GVHD in children. Potential mechanisms include increased intestinal permeability and increased lymphocyte homing to the intestine.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/20/2801/1400727/blood765826.pdf

Reference38 articles.

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4. From the diet to the nucleus: vitamin A and TGF-beta join efforts at the mucosal interface of the intestine;Mucida;Semin Immunol,2009

5. The effect of vitamin A on epithelial integrity;McCullough;Proc Nutr Soc,1999

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