Germline Missense Variants in SH2B3 Underpin Platelet Count Variation and Inherited MPN

Author:

Butler Liesl12,Lee Christine3,Magor Graham William1,Morris Rhiannon4,Tallack Michael56,Lam Charlene1,Ivey Adam7,Lin Jane8,Deng Zihao1,Grigg Andrew910,Mason Jane11,Perchard Malaika12,Weston Helen13,Cummings Nik141,Brooks Andrew15,Babon Jeffrey J16,Murphy Andrew J17,Salmon Jessica M1,Perkins Andrew Charles181918

Affiliation:

1. 1Australian Centre for Blood Diseases, Monash University, Melbourne, Australia

2. 2Department of Haematology, Alfred Hospital, Melbourne, Australia

3. 3Diamantina Institute, The University of Queensland, Woolloongabba, AUS

4. 4The Walter and Eliza Hall Institute of Medical Research, Melbourne University, Melbourne, Australia

5. 5Mater Research Institute - University of Queensland, Brisbane, Australia

6. 6Queensland Medical Laboratories, Brisbane, Australia

7. 7Molecular Pathology, The Alfred Hospital, Melbourne, Australia

8. 8Pathology, Alfred Hospital, Melbourne, Australia

9. 9Department of Haematology, Austin Health, Melbourne, Australia

10. 10Australasian Leukaemia and Lymphoma Group (ALLG), Melbourne, Australia

11. 11Queensland Haemophilia Centre, Cancer Care Services, Royal Brisbane and Women's Hospital, Brisbane, Australia

12. 12Royal Brisbane Women's and Children's Hospital, Brisbane, Australia

13. 13Haematology Department, Sunshine Coast University Hospital, Sunshione Coast, Australia

14. 14Pathology, Alfred Health, Melbourne, Australia

15. 15The University of Queensland, Brisbane, AUS

16. 16The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia

17. 17Haematopoiesis and Leukocyte Biology, Baker Heart and Diabetes Institute, Melbourne, Australia

18. 18Department of Haematology, Alfred Hospital, Melbourne, Australia

19. 19Australasian Leukaemia and Lymphoma Group (ALLG), Richmond, Australia

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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