Mast cells suppress murine GVHD in a mechanism independent of CD4+CD25+ regulatory T cells-Reference-Cited by-同舟云学术

Mast cells suppress murine GVHD in a mechanism independent of CD4+CD25+ regulatory T cells

Published:2013-11-21 Issue:22 Volume:122 Page:3659-3665
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Leveson-Gower Dennis B.¹,Sega Emanuela I.¹,Kalesnikoff Janet²,Florek Mareike¹,Pan Yuqiong¹,Pierini Antonio¹,Galli Stephen J.²,Negrin Robert S.¹

Affiliation:

1. School of Medicine, Division of Bone Marrow Transplant, and

2. Department of Pathology, Stanford University, Stanford, CA

Abstract

Key Points Mice lacking mast cells have severely exacerbated GVHD compared with WT controls. Engraftment of mast cells into C75BL/6-KitW-sh/W-sh mast cell–deficient animals improves survival but not if the mast cells are derived from IL-10 KO mice.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/22/3659/1371578/3659.pdf

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5. Murine graft-versus-host skin disease: a chronologic and quantitative analysis of two histologic patterns.;Charley;J Invest Dermatol,1983

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