Structure of the factor VIII C2 domain in a ternary complex with 2 inhibitor antibodies reveals classical and nonclassical epitopes
Author:
Affiliation:
1. Western Washington University, Department of Chemistry, Bellingham, WA; and
2. Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University, Atlanta, GA
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/122/26/4270/1372703/4270.pdf
Reference60 articles.
1. The future of plasma-derived clotting factor concentrates.;Hoots;Haemophilia,2001
2. Purity of factor VIII product and incidence of inhibitors in previously untreated patients with haemophilia A.;Mauser-Bunschoten;Haemophilia,2001
3. Incidence of inhibitors in haemophilia A patients—a review of recent studies of recombinant and plasma-derived factor VIII concentrates.;Scharrer;Haemophilia,1999
4. A multicenter study of recombinant factor VIII (recombinate): safety, efficacy, and inhibitor risk in previously untreated patients with hemophilia A.;Bray;Blood,1994
5. Inhibitor development in previously untreated patients with hemophilia A: a prospective long-term follow-up comparing plasma-derived and recombinant products.;Kreuz;Semin Thromb Hemost,2002
Cited by 24 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII;Frontiers in Molecular Biosciences;2022-10-26
2. Structural insights into blood coagulation factor VIII: Procoagulant complexes, membrane binding, and antibody inhibition;Journal of Thrombosis and Haemostasis;2022-09
3. Translational readthrough at <i>F8</i> nonsense variants in the factor VIII B domain contributes to residual expression and lowers inhibitor association;Haematologica;2022-08-04
4. Illustrated State‐of‐the‐Art Capsules of the ISTH 2021 Congress;Research and Practice in Thrombosis and Haemostasis;2021-07
5. Structure of Blood Coagulation Factor VIII in Complex With an Anti-C2 Domain Non-Classical, Pathogenic Antibody Inhibitor;Frontiers in Immunology;2021-06-10
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3