Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies-Reference-Cited by-同舟云学术

Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies

Published:2014-01-30 Issue:5 Volume:123 Page:678-686
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Kohrt Holbrook E.¹,Thielens Ariane²,Marabelle Aurelien¹³,Sagiv-Barfi Idit¹,Sola Caroline²,Chanuc Fabien²,Fuseri Nicolas²,Bonnafous Cécile²,Czerwinski Debra¹,Rajapaksa Amanda¹,Waller Erin¹,Ugolini Sophie³,Vivier Eric⁴,Romagné François²,Levy Ronald¹,Bléry Mathieu²,André Pascale²

Affiliation:

1. Department of Medicine, Division of Oncology, Stanford University, Stanford, CA;

2. Innate Pharma, Marseille, France;

3. Centre de Recherche en Cancérologie de Lyon, Centre Léon Bérard, Université de Lyon, Lyon, France; and

4. Centre d’Immunologie de Marseille-Luminy, Aix Marseille Université UM2, Parc scientifique et technologique de Luminy, Marseille, France

Abstract

Key Points Blockade of inhibitory KIRs with MHC class I antigens on lymphoma cells by anti-KIR antibodies augments NK-cell spontaneous cytotoxicity. In combination with anti-CD20 mAbs, anti-KIR induces enhanced NK cell–mediated, rituximab-dependent cytotoxicity against lymphoma.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/123/5/678/1378113/678.pdf

Reference46 articles.

1. The blockade of immune checkpoints in cancer immunotherapy.;Pardoll;Nat Rev Cancer,2012

2. CD28 and CTLA-4 coreceptor expression and signal transduction.;Rudd;Immunol Rev,2009

3. Improved survival with ipilimumab in patients with metastatic melanoma.;Hodi;N Engl J Med,2010

4. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer.;Topalian;N Engl J Med,2012

5. Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape.;Woo;Cancer Res,2012

Cited by 237 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Immune cells in the B-cell lymphoma microenvironment: From basic research to clinical applications;Chinese Medical Journal;2024-01-25

2. MHC-I upregulation safeguards neoplastic T cells in the skin against NK cell-mediated eradication in mycosis fungoides;Nature Communications;2024-01-25

3. NK cell exhaustion in the tumor microenvironment;Frontiers in Immunology;2023-11-02

4. The Function of NK Cells in Tumor Metastasis and NK Cell-Based Immunotherapy;Cancers;2023-04-16

5. Lenalidomide maintenance fails to overcome the unfavourable prognosis of low NK‐cell counts in rituximab–chemotherapy responsive elderly DLBCL patients: A LYSA group study;British Journal of Haematology;2023-02-06