Low ADAMTS13 activity is associated with an increased risk of ischemic stroke-Reference-Cited by-同舟云学术

Low ADAMTS13 activity is associated with an increased risk of ischemic stroke

Published:2015-12-17 Issue:25 Volume:126 Page:2739-2746
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Sonneveld Michelle A. H.¹²,de Maat Moniek P. M.¹^ORCID,Portegies Marileen L. P.²³,Kavousi Maryam³,Hofman Albert³,Turecek Peter L.⁴,Rottensteiner Hanspeter⁴,Scheiflinger Fritz⁴,Koudstaal Peter J.²,Ikram M. Arfan²³⁵,Leebeek Frank W. G.¹

Affiliation:

1. Department of Hematology,

2. Department of Neurology, and

3. Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands;

4. Baxter Innovations GmbH, Vienna, Austria; and

5. Department of Radiology, Erasmus University Medical Center, Rotterdam, The Netherlands

Abstract

Key Points Low ADAMTS13 activity is associated with ischemic stroke. ADAMTS13 activity improved the accuracy of ischemic stroke risk predictions beyond the traditional risk factors.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/126/25/2739/1390102/2739.pdf

Reference36 articles.

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3. Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura.;Zheng;J Biol Chem,2001

4. Partial amino acid sequence of purified von Willebrand factor-cleaving protease.;Gerritsen;Blood,2001

5. High von Willebrand factor levels increase the risk of stroke: the Rotterdam study.;Wieberdink;Stroke,2010

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