Administration of interleukin-7 increases CD4 T cells in idiopathic CD4 lymphocytopenia-Reference-Cited by-同舟云学术

Administration of interleukin-7 increases CD4 T cells in idiopathic CD4 lymphocytopenia

Published:2016-02-25 Issue:8 Volume:127 Page:977-988
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Sheikh Virginia¹^ORCID,Porter Brian O.¹,DerSimonian Rebecca¹,Kovacs Stephen B.²,Thompson William L.¹,Perez-Diez Ainhoa¹,Freeman Alexandra F.¹,Roby Gregg¹,Mican JoAnn¹,Pau Alice¹,Rupert Adam²,Adelsberger Joseph²,Higgins Jeanette²,Bourgeois Jeffrey S.¹,Jensen Stig M. R.¹,Morcock David R.³,Burbelo Peter D.⁴,Osnos Leah¹,Maric Irina⁵,Natarajan Ven²,Croughs Therese⁶,Yao Michael D.¹,Estes Jacob D.³,Sereti Irini¹

Affiliation:

1. National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Bethesda, MD;

2. Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD;

3. AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD;

4. Dental Clinical Research Core, National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD;

5. Hematology Section, Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, MD; and

6. Cytheris Inc., Subsidiary of Cytheris S.A., Issy les Moulineaux, France

Abstract

Key Points rhIL-7 therapy was well tolerated in patients with ICL. rhIL-7 led to increases in CD4 T cells in both peripheral blood and tissues.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/127/8/977/1394965/977.pdf

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