Aggf1 acts at the top of the genetic regulatory hierarchy in specification of hemangioblasts in zebrafish-Reference-Cited by-同舟云学术

Aggf1 acts at the top of the genetic regulatory hierarchy in specification of hemangioblasts in zebrafish

Published:2014-01-23 Issue:4 Volume:123 Page:501-508
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Li Lei¹,Chen Di¹,Li Jia¹,Wang Xiaojing¹,Wang Nan¹,Xu Chengqi¹,Wang Qing K.¹²³

Affiliation:

1. Key Laboratory of Molecular Biophysics of the Ministry of Education, Department of Genetics and Developmental Biology, College of Life Science and Technology, Center for Human Genome Research, Cardio-X Institute, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; and

2. Center for Cardiovascular Genetics and

3. Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH

Abstract

Key PointsAggf1 is required for both primitive and definitive hematopoiesis. Aggf1 is the earliest known regulator for differentiation of hemangioblasts.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/123/4/501/1378503/501.pdf

Reference54 articles.

1. Hemangioblast development and regulation.;Choi;Biochem Cell Biol,1998

2. A common precursor for hematopoietic and endothelial cells.;Choi;Development,1998

3. Molecular and developmental biology of the hemangioblast.;Xiong;Dev Dyn,2008

4. Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures.;Kennedy;Blood,2007

5. Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages.;Nishikawa;Development,1998

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