Therapy-related acute myeloid leukemia and myelodysplastic syndromes in patients with Hodgkin lymphoma: a report from the German Hodgkin Study Group

Author:

Eichenauer Dennis A.12,Thielen Indra12,Haverkamp Heinz12,Franklin Jeremy3,Behringer Karolin12,Halbsguth Teresa12,Klimm Beate12,Diehl Volker2,Sasse Stephanie12,Rothe Achim12,Fuchs Michael12,Böll Boris12,von Tresckow Bastian12,Borchmann Peter12,Engert Andreas12

Affiliation:

1. First Department of Internal Medicine,

2. The German Hodgkin Study Group, and

3. The Institute of Medical Statistics, Informatics and Epidemiology, University Hospital of Cologne, Cologne, Germany

Abstract

Key Points Occurrence of t-AML/MDS after Hodgkin lymphoma is a rare event correlating with the intensity of first-line chemotherapy. Allogeneic stem cell transplantation appears to improve the generally poor prognosis of patients with t-AML/MDS after Hodgkin lymphoma.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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