PANORAMA 2: panobinostat in combination with bortezomib and dexamethasone in patients with relapsed and bortezomib-refractory myeloma

Author:

Richardson Paul G.1,Schlossman Robert L.1,Alsina Melissa2,Weber Donna M.3,Coutre Steven E.4,Gasparetto Cristina5,Mukhopadhyay Sutapa6,Ondovik Michael S.6,Khan Mahmudul6,Paley Carole S.6,Lonial Sagar7

Affiliation:

1. Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA;

2. H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL;

3. The University of Texas MD Anderson Cancer Center, Houston, TX;

4. Stanford Cancer Center and Stanford University School of Medicine, Palo Alto, CA;

5. Duke University Medical Center, Durham, NC;

6. Novartis Pharmaceuticals Corporation, East Hanover, NJ; and

7. Winship Cancer Institute, Emory University, Atlanta, GA

Abstract

Key PointsPanobinostat + bortezomib + dexamethasone recaptures responses in heavily pretreated, bortezomib-refractory multiple myeloma patients.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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