Ubiquitin-mediated interaction of p210 BCR/ABL with β-catenin supports disease progression in a murine model for chronic myelogenous leukemia-Reference-Cited by-同舟云学术

Ubiquitin-mediated interaction of p210 BCR/ABL with β-catenin supports disease progression in a murine model for chronic myelogenous leukemia

Published:2013-09-19 Issue:12 Volume:122 Page:2114-2124
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Chen Ru¹,Hu Tinghui¹,Mahon Gwendolyn M.¹,Tala Ilona¹,Pannucci Nicole L.¹,Ozer Harvey L.¹,Whitehead Ian P.¹

Affiliation:

1. Department of Microbiology and Molecular Genetics and New Jersey Medical School-University Hospital Cancer Center, University of Medicine and Dentistry of New Jersey, Newark, NJ

Abstract

Key Points p210 BCR/ABL interacts with β-catenin in the bone marrow transplantation model for chronic myelogenous leukemia. Loss of the interaction results in an altered disease phenotype, suggesting a role for β-catenin in chronic phase disease.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/12/2114/1369440/2114.pdf

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