Innate immune control of EBV-infected B cells by invariant natural killer T cells-Reference-Cited by-同舟云学术

Innate immune control of EBV-infected B cells by invariant natural killer T cells

Published:2013-10-10 Issue:15 Volume:122 Page:2600-2608
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Chung Brian K.¹,Tsai Kevin¹,Allan Lenka L.¹,Zheng Dong Jun¹,Nie Johnny C.¹,Biggs Catherine M.¹,Hasan Mohammad R.¹,Kozak Frederick K.²,van den Elzen Peter¹,Priatel John J.¹,Tan Rusung¹

Affiliation:

1. Child and Family Research Institute, Immunity in Health and Disease, and Department of Pathology and Laboratory Medicine, University of British Columbia and British Columbia Children’s Hospital, Vancouver, BC, Canada; and

2. Division of Pediatric Otolaryngology, British Columbia Children’s Hospital, Vancouver, BC, Canada

Abstract

Key Points B cells rapidly downregulate CD1d expression after EBV infection, thus abrogating iNKT cell recognition. EBV-infected B cells induced to express CD1d elicit iNKT cell functions even in the absence of exogenous antigen.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/15/2600/1369219/2600.pdf

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