MicroRNA-139-5p regulates proliferation of hematopoietic progenitors and is repressed during BCR-ABL–mediated leukemogenesis-Reference-Cited by-同舟云学术

MicroRNA-139-5p regulates proliferation of hematopoietic progenitors and is repressed during BCR-ABL–mediated leukemogenesis

Published:2016-10-27 Issue:17 Volume:128 Page:2117-2129
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Choi Jinwook¹,Kim Young-Kook¹²,Park Kyungsoo¹,Nah Jinwoo¹,Yoon Sung-Soo³,Kim Dong-Wook⁴,Kim V. Narry¹²,Seong Rho Hyun¹

Affiliation:

1. School of Biological Sciences, Institute for Molecular Biology and Genetics,

2. Center for RNA Research, Institute for Basic Science, and

3. Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea; and

4. Department of Hematology, Seoul St. Mary's Hospital, Leukemia Research Institute, The Catholic University of Korea, Seoul, Korea

Abstract

Key Points Expression of miR-139-5p is downregulated in BCR-ABL–mediated CML patients. miR-139-5p regulates proliferation and differentiation activities by targeting Brg1 in early hematopoiesis.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/128/17/2117/1396273/2117.pdf

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