ADAMTS13-mediated thrombolysis of t-PA–resistant occlusions in ischemic stroke in mice-Reference-Cited by-同舟云学术

ADAMTS13-mediated thrombolysis of t-PA–resistant occlusions in ischemic stroke in mice

Published:2016-05-12 Issue:19 Volume:127 Page:2337-2345
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Denorme Frederik¹,Langhauser Friederike²,Desender Linda¹,Vandenbulcke Aline¹,Rottensteiner Hanspeter³,Plaimauer Barbara³,François Olivier⁴,Andersson Tommy⁴⁵,Deckmyn Hans¹^ORCID,Scheiflinger Friedrich³,Kleinschnitz Christoph²,Vanhoorelbeke Karen¹,De Meyer Simon F.¹

Affiliation:

1. Laboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium;

2. Department of Neurology, University Clinic of Würzburg, Würzburg, Germany;

3. Baxalta Innovations GmbH, Vienna, Austria;

4. Department of Medical Imaging, AZ Groeninge, Kortrijk, Belgium; and

5. Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden

Abstract

Key Points ADAMTS13 dissolves t-PA–resistant cerebral occlusions in a mouse model of stroke. The thrombolytic activity of ADAMTS13 could become useful for more efficient and safer thrombolytic treatment of acute ischemic stroke.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/127/19/2337/1393356/2337.pdf

Reference44 articles.

1. The impact of recanalization on ischemic stroke outcome: a meta-analysis.;Rha;Stroke,2007

2. Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials.;Emberson;Lancet,2014

3. Impact of tissue plasminogen activator on the neurovascular unit: from clinical data to experimental evidence.;Vivien;J Cereb Blood Flow Metab,2011

4. Length of occlusion predicts recanalization and outcome after intravenous thrombolysis in middle cerebral artery stroke.;Rohan;Stroke,2014

5. Distance to thrombus in acute middle cerebral artery occlusion: a predictor of outcome after intravenous thrombolysis for acute ischemic stroke.;Friedrich;Stroke,2015

Cited by 147 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Targeting neutrophils extracellular traps, a promising anti-thrombotic therapy for natural products from traditional Chinese herbal medicine;Biomedicine & Pharmacotherapy;2024-10

2. Inhibition of neutrophil rolling and migration by caADAMTS13 in vitro and in mouse models of thrombosis and inflammation;Biomedicine & Pharmacotherapy;2024-09

3. Effect of Danhong Injection on Pharmacokinetics and Pharmacodynamics of Rivaroxaban in Rats;2024-08-19

4. Relationship between thrombus composition and prognosis in patients with acute ischemic stroke undergoing mechanical thrombectomy;Journal of Clinical Neuroscience;2024-08

5. Acute Ischemic Stroke Thrombus Composition;Neuroscience;2024-07