Platelet transfusions in platelet consumptive disorders are associated with arterial thrombosis and in-hospital mortality

Author:

Goel Ruchika12,Ness Paul M.1,Takemoto Clifford M.2,Krishnamurti Lakshmanan3,King Karen E.1,Tobian Aaron A. R.1

Affiliation:

1. Division of Transfusion Medicine, Department of Pathology, and

2. Division of Pediatric Hematology, Johns Hopkins University, Baltimore, MD; and

3. Division of Pediatric Blood and Bone Marrow Transplantation, Emory University School of Medicine, Atlanta, GA

Abstract

Key Points Platelet transfusions are frequently administered to hospitalized patients with platelet consumptive/destructive disorders such as TTP, HIT, and ITP. Platelet transfusions are associated with higher odds of arterial thrombosis and mortality among TTP and HIT patients.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Reference51 articles.

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