Eradication of bone marrow minimal residual disease may prompt early treatment discontinuation in CLL

Author:

Strati Paolo1,Keating Michael J.1,O'Brien Susan M.1,Burger Jan1,Ferrajoli Alessandra1,Jain Nitin1,Tambaro Francesco Paolo2,Estrov Zeev1,Jorgensen Jeffrey3,Challagundla Pramoda3,Faderl Stefan H.1,Wierda William G.1

Affiliation:

1. Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX;

2. Dipartimento di Patologia Generale, Seconda Università degli Studi di Napoli, Napoli, Italy; and

3. Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX

Abstract

Key Points MRD eradication is a desirable end point in chronic lymphocytic leukemia. Early MRD eradication may prompt treatment discontinuation.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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