Results of an open-label multicenter phase 2 trial of lenalidomide monotherapy in refractory mycosis fungoides and Sézary syndrome-Reference-Cited by-同舟云学术

Results of an open-label multicenter phase 2 trial of lenalidomide monotherapy in refractory mycosis fungoides and Sézary syndrome

Published:2014-02-20 Issue:8 Volume:123 Page:1159-1166
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Querfeld Christiane¹,Rosen Steven T.²,Guitart Joan³,Duvic Madeleine⁴,Kim Youn H.⁵,Dusza Stephen W.¹,Kuzel Timothy M.²

Affiliation:

1. Department of Medicine/Dermatology Service, Memorial Sloan-Kettering Cancer Center, New York, NY;

2. Department of Medicine, Division of Hematology/Oncology and

3. Department of Dermatology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL;

4. Department of Dermatology, University of Texas, MD Anderson Cancer Center, Houston, TX; and

5. Department of Dermatology, Stanford University, Stanford, CA

Abstract

Key Points Lenalidomide is effective in refractory advanced cutaneous T-cell lymphoma, with an overall response rate of 28%. Patients demonstrate a transient flare reaction in skin, blood, and/or lymph nodes that may be associated with improvement in disease burden.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/123/8/1159/1378964/1159.pdf

Reference38 articles.

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4. A randomized trial comparing combination electron-beam radiation and chemotherapy with topical therapy in the initial treatment of mycosis fungoides.;Kaye;N Engl J Med,1989

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