Immune evasion by oncogenic proteins of acute myeloid leukemia-Reference-Cited by-同舟云学术

Immune evasion by oncogenic proteins of acute myeloid leukemia

Published:2014-03-06 Issue:10 Volume:123 Page:1535-1543
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Elias Shlomo¹²³,Yamin Rachel¹,Golomb Lior⁴,Tsukerman Pinchas¹,Stanietsky-Kaynan Noah¹,Ben-Yehuda Dina³,Mandelboim Ofer¹

Affiliation:

1. The Lautenberg Center for General and Tumor Immunology, Institute for Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel;

2. Department of Medicine and

3. Department of Hematology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel; and

4. Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel

Abstract

Key Points PML-RARA and AML1-ETO evade NK cell recognition by specifically downregulating the expression of CD48. The findings are relevant to AML patients bearing these specific translocations.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/123/10/1535/1375002/1535.pdf

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