UBTF tandem Duplications Account for a Third of Advanced Pediatric MDS without Genetic Predisposition to Myeloid Neoplasia

Author:

Erlacher Miriam12,Stasik Sebastian3,Yoshimi Ayami4,Georgi Julia-Annabell3,Göhring Gudrun5,Rudelius Martina6,Baumann Irith7,Schwarz-Furlan Stephan7,De Moerloose Barbara8,Hasle Henrik9,Masetti Riccardo10,Barzilai-Birenboim Shlomit11,Stary Jan12,Wlodarski Marcin W.413,Rotari Natalia4,Ramamoorthy Senthilkumar414,Lebrecht Dirk1,Noellke Peter4,Strahm Brigitte15,Niemeyer Charlotte M.42,Thiede Christian316

Affiliation:

1. 1Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany

2. 2partner site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany

3. 3Department of Internal Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany

4. 4Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Faculty of Medicine, University of Freiburg, Freiburg, Germany

5. 5Department of Human Genetics, Hannover Medical School, Hannover, Germany

6. 6Institute of Pathology, Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany

7. 7Institute of Pathology Kaufbeuren-Ravensburg, Kaufbeuren, Germany

8. 8Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, BEL

9. 9Department of Pediatrics, Aarhus University Hospital Skejby, Aarhus, Denmark

10. 10Pediatric Oncology and Hematology "Lalla Seràgnoli", IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy

11. 11Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

12. 12Dept. of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic

13. 13Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN

14. 14Institute of Medical Bioinformatics and Systems Medicine, Faculty of Medicine, University of Freiburg, Freiburg, Germany

15. 15Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany

16. 16German Cancer Research Center (DKFZ), Heidelberg, Germany

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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