Epstein-Barr virus: the impact of scientific advances on clinical practice-Reference-Cited by-同舟云学术

Epstein-Barr virus: the impact of scientific advances on clinical practice

Published:2006-02-01 Issue:3 Volume:107 Page:862-869
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Williams Hilary¹,Crawford Dorothy H.¹

Affiliation:

1. From the Department of Oncology, Bristol Royal Infirmary, Bristol, United Kingdom; and the Basic and Clinical Virology Laboratory, Centre for Infectious Diseases, University of Edinburgh, Edinburgh, United Kingdom.

Abstract

AbstractEpstein-Barr virus (EBV) is a tumorigenic herpes virus that infects and persists in B lymphocytes in the majority of humans, generally without causing disease. However, in a few individuals the virus is associated with significant pathology, particularly benign and malignant lymphoproliferations. Recently acquired knowledge on the mechanisms of EBV persistence, immune control of primary and persistent infection, and disease pathogenesis is now being translated into the clinic with novel methods of diagnosis, prevention and treatment contributing to improved patient care. This review concentrates on these recent advances in the field of hematology/oncology.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/107/3/862/1279882/zh800306000862.pdf

Reference106 articles.

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3. Pattengale PK, Smith RW, Gerber P. Selective transformation of B lymphocytes by EB virus. Lancet. 1973;2: 93-94.

4. Crawford DH. Biology and disease associations of Epstein-Barr virus. Philos Trans R Soc Lond B Biol Sci. 2001;356: 461-473.

5. Hoagland RJ. The transmission of infectious mononucleosis. Am J Med Sci. 1955;229: 262-272.

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