High prevalence of somatic MAP2K1 mutations in BRAF V600E–negative Langerhans cell histiocytosis
Author:
Affiliation:
1. Department of Pathology, University of Michigan Medical School, Ann Arbor, MI; and
2. Department of Pathology, University of Chicago, Chicago, IL
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/124/10/1655/1379704/1655.pdf
Reference21 articles.
1. Multisystem Langerhans cell histiocytosis in children: current treatment and future directions.;Minkov;Paediatr Drugs,2011
2. Recurrent BRAF mutations in Langerhans cell histiocytosis.;Badalian-Very;Blood,2010
3. BRAFV600E mutant protein is expressed in cells of variable maturation in Langerhans cell histiocytosis.;Sahm;Blood,2012
4. Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation.;Haroche;Blood,2013
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