Somatic mutations identify a subgroup of aplastic anemia patients who progress to myelodysplastic syndrome-Reference-Cited by-同舟云学术

Somatic mutations identify a subgroup of aplastic anemia patients who progress to myelodysplastic syndrome

Published:2014-10-23 Issue:17 Volume:124 Page:2698-2704
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Kulasekararaj Austin G.¹²,Jiang Jie¹²,Smith Alexander E.¹²,Mohamedali Azim M.¹²,Mian Syed¹,Gandhi Shreyans²,Gaken Joop¹,Czepulkowski Barbara²,Marsh Judith C. W.¹²,Mufti Ghulam J.¹²

Affiliation:

1. Department of Haematological Medicine, King’s College London School of Medicine, London, United Kingdom; and

2. Department of Haematology, King’s College Hospital, London, United Kingdom

Abstract

Key Points Acquired mutations of myeloid-related genes are present in a proportion of AA patients. Somatic mutations in AA predict higher risk of transformation to MDS.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/124/17/2698/1380359/2698.pdf

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