The effect of variation in donor platelet function on transfusion outcome: a semirandomized controlled trial-Reference-Cited by-同舟云学术

The effect of variation in donor platelet function on transfusion outcome: a semirandomized controlled trial

Published:2017-07-13 Issue:2 Volume:130 Page:214-220
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Kelly Anne M.¹,Garner Stephen F.¹²,Foukaneli Theodora²,Godec Thomas R.³,Herbert Nina¹,Kahan Brennan C.⁴,Deary Alison²,Bakrania Lekha²,Llewelyn Charlotte²,Ouwehand Willem H.¹²,Williamson Lorna M.¹²,Cardigan Rebecca A.¹²

Affiliation:

1. Department of Haematology, Cambridge Biomedical Campus, University of Cambridge, Cambridge, United Kingdom;

2. National Health Service Blood and Transplant, Cambridge, United Kingdom;

3. Medical Research Council Clinical Trials Unit at University College London, Institute of Clinical Trials and Methodology, London, United Kingdom; and

4. Pragmatic Clinical Trials Unit, Queen Mary University of London, London, United Kingdom

Abstract

Key Points There is variation in platelet function between normal individuals, and this function is consistent within the same individual over time. The data from this study suggest that variation in donor platelet function does not affect the outcome of prophylactic transfusion.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/130/2/214/1404060/blood759258.pdf

Reference25 articles.

1. Platelet transfusions for patients with haematological malignancies: who needs them?;Estcourt;Br J Haematol,2011

2. Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects;Fontana;Circulation,2003

3. Epinephrine-induced platelet aggregation. A twin study;Gaxiola;Clin Genet,1984

4. Mapping the platelet profile for functional genomic studies and demonstration of the effect size of the GP6 locus;Jones;J Thromb Haemost,2007

5. Platelet responses to agonists in a cohort of highly characterised platelet donors are consistent over time;Garner;Vox Sang,2017

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Donor Selection for Adults and Pediatrics;The EBMT Handbook;2024

2. The impact of donor biological variation on the quality and function of cold‐stored platelets;Vox Sanguinis;2023-07-13

3. How I use platelet transfusions;Blood;2022-11-03

4. Screening platelet function in blood donors;Transfusion;2022-06-24

5. Neonatal platelet transfusions: New evidence and the challenges of translating evidence‐based recommendations into clinical practice;Journal of Thrombosis and Haemostasis;2022-03