HO-1hi patrolling monocytes protect against vaso-occlusion in sickle cell disease-Reference-Cited by-同舟云学术

HO-1hi patrolling monocytes protect against vaso-occlusion in sickle cell disease

Published:2018-04-05 Issue:14 Volume:131 Page:1600-1610
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Liu Yunfeng¹,Jing Fangmiao¹,Yi Woelsung¹,Mendelson Avital¹,Shi Patricia¹,Walsh Ronald²,Friedman David F.³,Minniti Caterina⁴,Manwani Deepa⁵,Chou Stella T.³,Yazdanbakhsh Karina¹

Affiliation:

1. Laboratory of Complement Biology, New York Blood Center, New York, NY;

2. Division of Pathology, Montefiore Medical Center, Bronx, NY;

3. Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA; and

4. Division of Hematology, Department of Medicine, and

5. Department of Pediatrics, Albert Einstein College of Medicine, Bronx, NY

Abstract

Key Points SCD patients with a recent VOC episode have lower frequencies and numbers of HO-1hi patrolling monocytes. Heme-driven SCD vaso-occlusion is exacerbated in mice lacking patrolling monocytes and reversed following patrolling monocyte transfer.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/131/14/1600/1406022/blood819870.pdf

Reference46 articles.

1. Neutrophils, platelets, and inflammatory pathways at the nexus of sickle cell disease pathophysiology;Zhang;Blood,2016

2. Vasculopathy in sickle cell disease: Biology, pathophysiology, genetics, translational medicine, and new research directions;Kato;Am J Hematol,2009

3. Heme cytotoxicity and the pathogenesis of immune-mediated inflammatory diseases;Larsen;Front Pharmacol,2012

4. Heme degradation and vascular injury;Belcher;Antioxid Redox Signal,2010

5. Cardiovascular complications and risk of death in sickle-cell disease;Gladwin;Lancet,2016

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