A gene signature that distinguishes conventional and leukemic nonnodal mantle cell lymphoma helps predict outcome

Author:

Clot Guillem12ORCID,Jares Pedro123ORCID,Giné Eva124ORCID,Navarro Alba12ORCID,Royo Cristina12,Pinyol Magda12,Martín-Garcia David12ORCID,Demajo Santiago1ORCID,Espinet Blanca5,Salar Antonio6ORCID,Ferrer Ana6ORCID,Muntañola Ana7,Aymerich Marta23,Rauert-Wunderlich Hilka89,Jaffe Elaine S.10ORCID,Connors Joseph M.11ORCID,Gascoyne Randy D.11,Delabie Jan12ORCID,López-Guillermo Armando124ORCID,Ott German13,Wright George W.9,Staudt Louis M.9,Rosenwald Andreas89,Scott David W.11,Rimsza Lisa M.14,Beà Sílvia12ORCID,Campo Elías123ORCID

Affiliation:

1. Institute for Biomedical Research August Pi i Sunyer, Barcelona, Spain;

2. Centro de Investigación Biomédica en Red de Cáncer, Madrid, Spain;

3. Hematopathology Unit-Laboratory of Pathology, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain;

4. Hematology Department, Hospital Clinic of Barcelona, Barcelona, Spain;

5. Pathology Department and

6. Hematology Department, IMIM-Hospital del Mar, Barcelona, Spain;

7. Servei d'Hematologia, Hospital Mútua de Terrassa, Terrassa, Spain;

8. Institute of Pathology, University of Würzburg, Würzburg, Germany;

9. Comprehensive Cancer Center Mainfranken, Würzburg, Germany;

10. Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD;

11. Centre for Lymphoid Cancer, British Columbia Cancer Agency, Vancouver, BC, Canada;

12. Department of Pathology, Toronto General Hospital, Toronto, ON, Canada;

13. Department of Clinical Pathology, Robert-Bosch-Krankenhaus and Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; and

14. Department of Pathology, Mayo Clinic, Scottsdale, AZ

Abstract

Key Points A new molecular assay identifies conventional and leukemic nonnodal MCL with differing clinicobiological features. The integration of the novel assay with genetic alterations identifies subsets of MCL patients with different management and outcome.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Cited by 81 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3