Loss of PRDM11 promotes MYC-driven lymphomagenesis-Reference-Cited by-同舟云学术

Loss of PRDM11 promotes MYC-driven lymphomagenesis

Published:2015-02-19 Issue:8 Volume:125 Page:1272-1281
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Fog Cathrine Kolster¹,Asmar Fazila²,Côme Christophe¹,Jensen Klaus Thorleif¹,Johansen Jens Vilstrup¹,Kheir Tony Bou¹,Jacobsen Linda¹,Friis Carsten¹,Louw Alison¹,Rosgaard Louise¹,Øbro Nina Friesgaard³,Marquart Hanne Vibeke³,Anthonsen Kristian⁴,Braat Arie Koen⁵,van Lohuizen Maarten⁵,Ralfkiaer Elisabeth⁶,Grønbæk Kirsten¹²,Lund Anders Henrik¹^ORCID

Affiliation:

1. Biotech Research and Innovation Centre and Centre for Epigenetics, University of Copenhagen, Copenhagen, Denmark;

2. Department of Hematology,

3. Department of Clinical Immunology, and

4. Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark;

5. Division of Molecular Genetics, Netherlands Cancer Institute, Amsterdam, The Netherlands; and

6. Department of Pathology, Rigshospitalet, Copenhagen, Denmark

Abstract

Key Points Loss of Prdm11 accelerates MYC-driven lymphomagenesis. PRDM11 regulates transcription of target genes, including FOS and JUN.

Publisher

American Society of Hematology

Subject