Resolution of acute inflammation bridges the gap between innate and adaptive immunity

Author:

Newson Justine1,Stables Melanie1,Karra Efthimia1,Arce-Vargas Frederick2,Quezada Sergio2,Motwani Madhur1,Mack Matthias3,Yona Simon1,Audzevich Tatsiana1,Gilroy Derek W.1ORCID

Affiliation:

1. Division of Medicine, Centre for Clinical Pharmacology and Therapeutics, University College London, London, United Kingdom;

2. Research Department of Haematology, Cancer Immunology Unit, University College London Cancer Institute, London, United Kingdom; and

3. Universitätsklinikum Regensburg, Innere Medizin II/Nephrologie-Transplantation, Regensburg, Germany

Abstract

Key PointsResolving, but not hyperinflammatory stimuli create a microenvironment conducive for the optimal development of adaptive immunity. After onset and resolution, we introduce a third phase to acute inflammatory responses dominated by macrophages and lymphocytes.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3