The future of autologous stem cell transplantation in myeloma

Author:

van Rhee Frits1ORCID,Giralt Sergio2,Barlogie Bart1

Affiliation:

1. Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, AR; and

2. Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, Weill Cornell Medical College, New York, NY

Abstract

Abstract Autologous stem cell transplantation (ASCT) has long been considered frontline therapy for newly diagnosed myeloma patients. This Spotlight examines the role of ASCT in the era of novel drugs and argues that ASCT should continue to be considered for eligible patients. A combination of novel drugs with ASCT in a sequential treatment approach can attain long-term survival and perhaps cure a subset of patients. ASCT will likely remain an important platform to develop curative strategies in the foreseeable future.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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