Diagnostic and risk criteria for HSCT-associated thrombotic microangiopathy: a study in children and young adults-Reference-Cited by-同舟云学术

Diagnostic and risk criteria for HSCT-associated thrombotic microangiopathy: a study in children and young adults

Published:2014-07-24 Issue:4 Volume:124 Page:645-653
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Jodele Sonata¹,Davies Stella M.¹,Lane Adam¹,Khoury Jane²,Dandoy Christopher¹,Goebel Jens³,Myers Kasiani¹,Grimley Michael¹,Bleesing Jack¹,El-Bietar Javier¹,Wallace Gregory¹,Chima Ranjit S.⁴,Paff Zachary⁴,Laskin Benjamin L.⁵

Affiliation:

1. Division of Bone Marrow Transplantation and Immune Deficiency,

2. Division of Biostatistics and Epidemiology,

3. Division of Nephrology and Hypertension, and

4. Division of Critical Care Medicine, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH; and

5. Division of Nephrology, The Children’s Hospital of Philadelphia, Philadelphia, PA

Abstract

Key Points Proteinuria and elevated markers of complement activation at TMA diagnosis are associated with poor outcome. Clinical interventions should be considered in HSCT patients with these high-risk features at the time TMA is diagnosed.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/124/4/645/1381800/645.pdf

Reference42 articles.

1. Small vessels, big trouble in the kidneys and beyond: hematopoietic stem cell transplantation-associated thrombotic microangiopathy.;Laskin;Blood,2011

2. The role of endothelial cell injury in thrombotic microangiopathy.;Goldberg;Am J Kidney Dis,2010

3. The contribution of endothelial activation and injury to end-organ toxicity following allogeneic hematopoietic stem cell transplantation.;Cooke;Biol Blood Marrow Transplant,2008

4. Chronic kidney disease after pediatric hematopoietic cell transplant.;Hingorani;Biol Blood Marrow Transplant,2008

5. Biopsy-diagnosed renal disease in patients after transplantation of other organs and tissues.;Schwarz;Am J Transplant,2010

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