Oxidized low-density lipoproteins induce rapid platelet activation and shape change through tyrosine kinase and Rho kinase–signaling pathways-Reference-Cited by-同舟云学术

Oxidized low-density lipoproteins induce rapid platelet activation and shape change through tyrosine kinase and Rho kinase–signaling pathways

Published:2013-07-25 Issue:4 Volume:122 Page:580-589
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Wraith Katie S.¹,Magwenzi Simbarashe¹,Aburima Ahmed¹,Wen Yichuan²,Leake David²,Naseem Khalid M.¹

Affiliation:

1. Centre for Cardiovascular and Metabolic Research, Hull York Medical School, Thrombosis Research Laboratory, University of Hull, Hull, United Kingdom; and

2. School of Biological Sciences, University of Reading, Reading, United Kingdom

Abstract

Key Points Oxidized LDL stimulates rapid change in platelet shape through ligation of CD36. Ligation of CD36 by oxidized LDL simultaneously activates tyrosine and Rho kinase–dependent signaling pathways.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/4/580/1373152/580.pdf

Reference41 articles.

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5. Mildly oxidized LDL induces platelet aggregation through activation of phospholipase A2.;Weidtmann;Arterioscler Thromb Vasc Biol,1995

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