Tyrosine kinase inhibitor usage, treatment outcome, and prognostic scores in CML: report from the population-based Swedish CML registry

Author:

Höglund Martin1,Sandin Fredrik2,Hellström Karin2,Björeman Mats3,Björkholm Magnus4,Brune Mats5,Dreimane Arta6,Ekblom Marja7,Lehmann Sören4,Ljungman Per4,Malm Claes6,Markevärn Berit8,Myhr-Eriksson Kristina9,Ohm Lotta4,Olsson-Strömberg Ulla1,Själander Anders10,Wadenvik Hans5,Simonsson Bengt1,Stenke Leif4,Richter Johan7

Affiliation:

1. Department of Medical Science and Division of Hematology, University Hospital, Uppsala, Sweden;

2. Regional Cancer Centre, Uppsala-Örebro, Sweden;

3. Department of Hematology, University Hospital, Örebro, Sweden;

4. Department of Hematology, Karolinska University Hospital and Department of Medicine, Karolinska Institutet, Stockholm, Sweden;

5. Department of Hematology, Sahlgrenska University Hospital, Göteborg, Sweden;

6. Department of Hematology, University Hospital, Linköping, Sweden;

7. Department of Hematology and Coagulation, Skåne University Hospital, Lund, Sweden;

8. Department of Hematology, University Hospital, Umeå, Sweden;

9. Department of Hematology, Sunderby-Luleå Hospital, Luleå, Sweden; and

10. Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden

Abstract

Key Points Patients up to age 70 years with CML treated within a decentralized health care setting had a relative survival close to 1.0. Sokal, but not EUTOS, score at diagnosis predicted overall and relative survival in a population-based cohort of patients with CML.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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