Affiliation:
1. Center for Immunobiology and Vaccine Development, UCSF Benioff Children’s Hospital Oakland, Oakland, CA
Abstract
Key Points
Eculizumab, an anti–complement C5 mAb, blocked killing of meningococci by whole blood from healthy immunized adults. Blocking the AP with ACH-4471, a small molecule in development for PNH, had much less of an effect on meningococcal killing.
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Cited by
100 articles.
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