Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin
Author:
Affiliation:
1. Department of Pathology, Children's Hospital Boston, Boston, MA;
2. Departments of Pharmacology & Cancer Biology and Pediatrics, Duke University School of Medicine, Durham, NC; and
3. Department of Pathology, Harvard Medical School, Boston, MA
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/116/25/5679/1461935/zh805110005679.pdf
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3. Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis.;Roetto;Nat Genet,2003
4. The molecular basis of ferroportin-linkedhemochromatosis.;De Domenico;Proc Natl Acad Sci U S A,2005
5. In vitro functional analysis of human ferroportin (FPN) and hemochromatosis-associated FPN mutations.;Schimanski;Blood,2005
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