Visualization of the dynamics of fibrin clot growth 1 molecule at a time by total internal reflection fluorescence microscopy-Reference-Cited by-同舟云学术

Visualization of the dynamics of fibrin clot growth 1 molecule at a time by total internal reflection fluorescence microscopy

Published:2013-02-21 Issue:8 Volume:121 Page:1455-1458
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Hategan Alina¹,Gersh Kathryn C.¹,Safer Daniel²,Weisel John W.¹

Affiliation:

1. Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; and

2. Pennsylvania Muscle Institute, University of Pennsylvania, Philadelphia, PA

Abstract

Key PointsFibrin polymerization was observed for the first time at the single-molecule level by total internal reflection fluorescence microscopy. Live observation of fibrin polymerization with a single-molecule fluorescence intensity calibration revealed the real-time growth kinetics.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/8/1455/1369308/zh800813001455.pdf

Reference18 articles.

1. Fibrinogen and fibrin.;Weisel;Adv Protein Chem,2005

2. Assembly of fibrin. A light scattering study.;Hantgan;J Biol Chem,1979

3. Fibrin assembly: a comparison of electron microscopic and light scattering results.;Hantgan;Thromb Haemost,1980

4. Gel formation by fibrin oligomers without addition of monomers.;Janmey;Biopolymers,1986

5. Native fibrin gel networks observed by 3D microscopy, permeation and turbidity.;Blomback;Biochim Biophys Acta,1989

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